TX05 Provides Comparable DFS Benefit to Trastuzumab in Early-Stage HER2+ Breast Cancer

TX05 Provides Comparable DFS Benefit to Trastuzumab in Early-Stage HER2+ Breast Cancer

Adjuvant treatment with TX05 resulted in a similar disease-free survival benefit to that of trastuzumab in patients with early-stage HER2-positive breast cancer. Adjuvant treatment with TX05 resulted in a similar disease-free survival (DFS) benefit to that of trastuzumab (Herceptin) in patients with early-stage HER2-positive breast cancer, according to results from the phase 3 TX05-03e trial … Read more

Incredible Virus Discovery Offers Clues About the Origins of Complex Life

Incredible Virus Discovery Offers Clues About the Origins of Complex Life

“Origin of Life” artist’s concept. The first discovery of viruses infecting a group of microbes that may include the ancestors of all complex life has been found, scientists at The University of Texas at Austin (UT Austin) report in Nature Microbiology. The incredible discovery offers tantalizing clues about the origins of complex life and suggests … Read more

Hot Flashes From Hormone Therapy, Poorer Outcomes in Breast Cancer

Hot Flashes From Hormone Therapy, Poorer Outcomes in Breast Cancer

Patients with estrogen receptor–positive breast cancer are usually given adjuvant hormone therapy (AHT) to block estrogen. A common side effect of this therapy is hot flashes, but these are often so uncomfortable that they in turn require treatment. New findings from a large real-world study suggest that this may result in worse outcomes. The study … Read more

Mechanism for chloroplast protein translocation and quality control

Mechanism for chloroplast protein translocation and quality control

The proposed role of Orf2971 in chloroplast protein translocation. Credit: Xing Jiale and Zhang Zhongchun In a recent study published online in The Plant CellProf. Yang Wenqiang’s research team from the Institute of Botany of the Chinese Academy of Sciences (IBCAS) has reported the critical role of the largest protein Orf2971 encoded by the Chlamydomonas … Read more

Deep Vein Thrombosis, Pulmonary Embolism, and Bleeding Risk in COVID-19

Deep Vein Thrombosis, Pulmonary Embolism, and Bleeding Risk in COVID-19

An increased risk of deep vein thrombosis, pulmonary embolism, and bleeding may exist for individuals with COVID-19, according to study results published in the British Medical Journal. Previous conflicting reports concerning venous thromboembolism risk following COVID-19 led researchers to investigate the risk of deep vein thrombosis, pulmonary embolism, and bleeding following COVID-19. To accomplish this, … Read more